⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17623451 | 0.76 | — | — | |
| SCHEMBL8231380 | 0.72 | — | — | |
| SCHEMBL22061878 | 0.72 | — | — | |
| SCHEMBL24175014 | 0.70 | — | — | |
| SCHEMBL17623027 | 0.70 | — | — | |
| SCHEMBL15165960 | 0.70 | — | — | |
| SCHEMBL16091149 | 0.69 | — | — | |
| SCHEMBL10264721 | 0.68 | — | — | |
| SCHEMBL17622761 | 0.67 | TDP1 (0.32) | — | |
| SCHEMBL19477287 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014144169-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-18 | — | — | WO | disclosed |