SCHEMBL16093375

SCHEMBL16093375

Cc1cccc(Cn2nc(C3CC3)c3c(NC(=O)c4cnc5cc(OCCN6CC[N+](C)(O)CC6)ccn45)cccc32)n1

nearest known ligand 0.90

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 20/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2052567 0.94 CSF1R (1.00) CSF1R
SCHEMBL2050389 0.93 CSF1R (1.00) CSF1R
SCHEMBL2050855 0.93 CSF1R (1.00) CSF1R
Arry-382 SCHEMBL2048345 0.93 CSF1R (1.00) CSF1R
Arry-382 SCHEMBL29370287 0.93 CSF1R (1.00) CSF1R
Arry-382 SCHEMBL30772280 0.93 CSF1R (1.00) CSF1R
SCHEMBL2047205 0.91 CSF1R (1.00) CSF1R
SCHEMBL2046796 0.91 CSF1R (1.00) CSF1R
SCHEMBL12641744 0.91 CSF1R (1.00) CSF1R
SCHEMBL2047858 0.90 CSF1R (1.00) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8841455-B2 Substituted N-(1H-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide compounds as cFMS inhibitors ARRAY BIOPHARMA INC. (US) 2014-09-23 US disclosed