Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 19/20 | 0.61 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.61 |
| ▸ | KDM5A | P29375 | 6/20 | 0.58 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.57 |
| ▸ | KDM4A | O75164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18159118 | 0.82 | KDM4C (0.77) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16075658 | 0.80 | KDM4C (0.80) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16095243 | 0.76 | KDM4C (0.64) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16033602 | 0.76 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16034477 | 0.74 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16034058 | 0.73 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5B | |
| SCHEMBL16034818 | 0.73 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16033793 | 0.73 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16033893 | 0.73 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16033706 | 0.73 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |