Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 14/20 | 0.57 |
| ▸ | KDM4A | O75164 | 8/20 | 0.57 |
| ▸ | KDM5B | Q9UGL1 | 8/20 | 0.57 |
| ▸ | KDM5A | P29375 | 7/20 | 0.57 |
| ▸ | KDM5C | P41229 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.45 |
| ▸ | KDM3A | Q9Y4C1 | 4/20 | 0.45 |
| ▸ | KDM6B | O15054 | 3/20 | 0.45 |
| ▸ | KDM4B | O94953 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095193 | 0.94 | KDM4C (0.59) | KDM4CKDM4AKDM5BKDM5AKDM5C | |
| SCHEMBL16094928 | 0.85 | KDM5C (0.55) | KDM4CKDM4AKDM5BKDM5AKDM5C | |
| SCHEMBL16094521 | 0.81 | KDM5B (0.59) | KDM4CKDM4AKDM5BKDM5AKDM5C | |
| SCHEMBL16095566 | 0.80 | KDM4C (0.61) | KDM4CKDM4AKDM5BKDM5AKDM5C | |
| SCHEMBL16094800 | 0.80 | KDM4C (0.61) | KDM4CKDM4AKDM5BKDM5AKDM5C | |
| SCHEMBL16096062 | 0.79 | KDM4C (0.54) | KDM4CKDM4AKDM5BKDM5AKDM5C | |
| SCHEMBL16095770 | 0.78 | KDM5B (0.45) | KDM4CKDM4AKDM5BKDM5AKDM5C | |
| SCHEMBL16102028 | 0.78 | KDM4C (0.44) | KDM4CKDM4AKDM5BKDM5AKDM5C | |
| SCHEMBL16095768 | 0.78 | KDM4C (0.44) | KDM4CKDM4AKDM5BKDM5AKDM5C | |
| SCHEMBL16095232 | 0.78 | KDM4C (0.48) | KDM4CKDM5BKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |