Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 15/20 | 0.60 |
| ▸ | KDM5A | P29375 | 2/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095315 | 0.90 | KDM4C (0.60) | KDM4CKDM5AKDM2BKDM5BKDM4A | |
| SCHEMBL16103402 | 0.84 | KDM4C (0.59) | KDM4CKDM5AKDM2BKDM5BKDM4A | |
| SCHEMBL16094728 | 0.80 | KDM4C (0.64) | KDM4CKDM5AKDM2BMAPK14GSK3B | |
| SCHEMBL16094861 | 0.80 | KDM4C (0.62) | KDM4CKDM5AKDM2BMAPK14GSK3B | |
| SCHEMBL16094974 | 0.79 | KDM4C (0.56) | KDM4CKDM5AKDM2BMAPK14GSK3B | |
| SCHEMBL16094741 | 0.78 | MAPK14 (0.48) | MAPK14GSK3BGSK3A | |
| SCHEMBL16032983 | 0.75 | KDM4C (1.00) | KDM4CKDM5AKDM2BMAPK14 | |
| SCHEMBL1387719 | 0.74 | MAPK14 (0.62) | MAPK14GSK3B | |
| SCHEMBL16095130 | 0.74 | KDM4C (0.69) | KDM4CKDM5AKDM2BKDM5B | |
| SCHEMBL1387759 | 0.73 | MAPK14 (0.55) | MAPK14GSK3BGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |