Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609147 | 0.92 | PDE10A (0.50) | PDE10AALDH1A1PDE4BPDE4DDRD2 | |
| SCHEMBL1609451 | 0.91 | PDE10A (0.52) | PDE10APDE4BPDE4DCHRM3PDE4A | |
| SCHEMBL1609831 | 0.90 | PDE10A (0.48) | PDE10APDE4BPDE4DCHRM3PDE4A | |
| SCHEMBL1609715 | 0.90 | PDE10A (0.48) | PDE10AALDH1A1PDE4BPDE4DCHRM3 | |
| SCHEMBL1610899 | 0.90 | PDE10A (0.48) | PDE10AALDH1A1PDE4BPDE4DCHRM3 | |
| SCHEMBL1609704 | 0.90 | PDE10A (0.62) | PDE10ACA1CA2ALDH1A1PDE4B | |
| SCHEMBL1613172 | 0.89 | PDE10A (0.47) | PDE10AALDH1A1PDE4BPDE4DCNR1 | |
| SCHEMBL1609755 | 0.89 | PDE10A (0.63) | PDE10APDE4BPDE4DCHRM3PDE4A | |
| SCHEMBL1610706 | 0.88 | PDE10A (0.47) | PDE10AALDH1A1PDE4BPDE4DCHRM3 | |
| SCHEMBL1609710 | 0.87 | PDE10A (0.47) | PDE10APDE4BPDE4DCNR1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | PDE10A 1704/4885CA1 3810/4885CA2 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.