Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.34 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.34 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.34 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.34 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.34 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.34 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.34 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713120 | 0.87 | PDE10A (0.37) | PDE10AMAPK1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL12713129 | 0.87 | PDE10A (0.37) | PDE10AMAPK1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL1609732 | 0.87 | PDE10A (0.39) | PDE10AMAPK1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL11903080 | 0.86 | PDE10A (0.36) | PDE10AMAPK1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL1610170 | 0.86 | PDE10A (0.50) | PDE10AMAPK1TSHRALDH1A1KDM4E | |
| SCHEMBL1609362 | 0.84 | PDE10A (0.40) | PDE10AMAPK1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL1611523 | 0.83 | EGFR (0.39) | PDE10AMAPK1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL1609921 | 0.83 | PDE10A (0.38) | PDE10AMAPK1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL12713157 | 0.83 | PDE10A (0.38) | PDE10AMAPK1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL1609871 | 0.83 | EGFR (0.39) | PDE10AMAPK1TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | PDE10A 1704/4885MAPK1 1418/4885TSHR 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.