Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16100158 | 0.90 | SCN9A (0.45) | SCN9A | |
| SCHEMBL17509684 | 0.86 | SCN9A (0.45) | SCN9A | |
| SCHEMBL1094007 | 0.84 | SCN9A (0.48) | SCN9A | |
| SCHEMBL17509689 | 0.83 | SCN9A (0.45) | SCN9A | |
| SCHEMBL9924648 | 0.79 | SCN9A (0.45) | SCN9A | |
| SCHEMBL16011228 | 0.76 | SCN9A (0.52) | SCN9A | |
| SCHEMBL10185423 | 0.76 | SCN9A (0.51) | SCN9A | |
| SCHEMBL10185455 | 0.76 | SCN9A (0.49) | SCN9A | |
| SCHEMBL29736437 | 0.76 | SCN9A (0.40) | SCN9A | |
| SCHEMBL1093593 | 0.76 | SCN9A (0.40) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193610-A1 | SELECTIVE NAV1.7 INHIBITORS FOR THE TREATMENT OF DIABETES | Chromocell Corporation (US) | 2017-07-26 | — | — | EP | disclosed |
| EP-3043787-A2 | SODIUM CHANNEL MODULATORS FOR THE TREATMENT OF PAIN AND DIABETES | Chromocell Corporation (US) | 2016-07-20 | — | — | EP | disclosed |
| WO-2016040315-A1 | SELECTIVE NAV1.7 INHIBITORS FOR THE TREATMENT OF DIABETES | CHROMOCELL CORPORATION (US) | 2016-03-17 | — | — | WO | disclosed |
| EP-2968234-A1 | SODIUM CHANNEL MODULATORS FOR THE TREATMENT OF PAIN | Chromocell Corporation (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151472-A1 | SODIUM CHANNEL MODULATORS FOR THE TREATMENT OF PAIN | CHROMOCELL CORPORATION (US) | 2014-09-25 | — | — | WO | disclosed |