Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 18/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16100677 | 0.79 | NPC1 (0.35) | — | |
| SCHEMBL30793646 | 0.71 | GRM5 (0.30) | GRM5 | |
| SCHEMBL13455921 | 0.70 | — | — | |
| SCHEMBL12285743 | 0.69 | HDAC6 (0.52) | GRM5 | |
| SCHEMBL6104496 | 0.69 | — | — | |
| SCHEMBL24536068 | 0.68 | NR1H2 (0.41) | GRM5 | |
| SCHEMBL30793197 | 0.68 | NR1H2 (0.41) | GRM5 | |
| SCHEMBL30793429 | 0.68 | MEN1 (0.42) | GRM5 | |
| SCHEMBL18183945 | 0.67 | GRM5 (0.33) | GRM5 | |
| SCHEMBL30793320 | 0.67 | NR1H2 (0.40) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970302-A1 | S1P AND/OR ATX MODULATING AGENTS | Biogen MA Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014152725-A1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-09-25 | — | — | WO | disclosed |