Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 18/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12712903 | 0.85 | PDE10A (0.67) | PDE10ACYP3A4CYP2D6NR1I2 | |
| SCHEMBL1610743 | 0.82 | KCNA5 (0.49) | PDE10AALDH1A1 | |
| SCHEMBL1610084 | 0.81 | PDE10A (0.56) | PDE10ACYP3A4CYP2D6NR1I2ALDH1A1 | |
| SCHEMBL12712782 | 0.81 | PDE10A (0.46) | PDE10ACYP3A4CYP2D6NR1I2 | |
| SCHEMBL1609451 | 0.81 | PDE10A (0.52) | PDE10ACYP3A4CYP2D6NR1I2 | |
| SCHEMBL12712766 | 0.81 | PDE10A (0.49) | PDE10ACYP3A4CYP2D6NR1I2 | |
| SCHEMBL12712900 | 0.81 | PDE10A (0.42) | PDE10ACYP3A4CYP2D6NR1I2 | |
| SCHEMBL1609372 | 0.81 | PDE10A (0.43) | PDE10ACYP3A4CYP2D6NR1I2ALDH1A1 | |
| SCHEMBL1609687 | 0.79 | PDE10A (0.45) | PDE10ACYP3A4CYP2D6NR1I2ALDH1A1 | |
| SCHEMBL1609704 | 0.79 | PDE10A (0.62) | PDE10ACYP3A4CYP1A2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | PDE10A 1704/4885CYP3A4 286/4885CYP2D6 231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.