Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.51 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30939882 | 1.00 | HASPIN (0.51) | HASPINDYRK2POLBCXCR4OPRM1 | |
| SCHEMBL30939934 | 0.86 | HASPIN (0.71) | HASPINDYRK2DYRK1A | |
| SCHEMBL16102858 | 0.86 | HASPIN (0.71) | HASPINDYRK2DYRK1A | |
| SCHEMBL16101182 | 0.85 | DYRK1A (0.51) | HASPINDYRK1A | |
| SCHEMBL30939927 | 0.85 | DYRK1A (0.51) | HASPINDYRK1A | |
| SCHEMBL15236151 | 0.83 | DYRK1A (0.49) | HASPINDYRK1A | |
| SCHEMBL15227864 | 0.82 | HASPIN (0.72) | HASPINDYRK2DYRK1A | |
| SCHEMBL30939871 | 0.82 | HASPIN (0.72) | HASPINDYRK2DYRK1A | |
| SCHEMBL30939873 | 0.77 | HASPIN (0.52) | HASPINDYRK2 | |
| SCHEMBL16123619 | 0.77 | HASPIN (0.52) | HASPINDYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113416187-A | Alkylamine peganine derivatives for promoting bone growth | 奥斯特克有限公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-105120863-B | Alkylamine peganine derivatives for promoting bone growth | 奥斯特克有限公司 | 2021-06-04 | — | — | CN | disclosed |
| EP-2968284-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | Osteoqc Inc. (CA) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153203-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | WO | disclosed |