Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 7/20 | 0.70 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.70 |
| ▸ | DYRK1A | Q13627 | 14/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16123628 | 0.83 | HASPIN (0.66) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL30940008 | 0.83 | HASPIN (0.66) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL12287315 | 0.82 | HASPIN (1.00) | HASPINDYRK2DYRK1A | |
| SCHEMBL30939968 | 0.82 | HASPIN (0.70) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL16102319 | 0.82 | HASPIN (0.70) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL16123609 | 0.81 | DYRK1A (0.72) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL30939975 | 0.81 | DYRK1A (0.72) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL16123615 | 0.80 | HASPIN (0.67) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL16123595 | 0.80 | HASPIN (0.73) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL30940011 | 0.80 | HASPIN (0.67) | HASPINDYRK2DYRK1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968284-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | Osteoqc Inc. (CA) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153203-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | WO | disclosed |