Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16103548 | 1.00 | HTR2C (0.36) | HTR2CSLC6A4NPC1ALDH1A1RAB9A | |
| SCHEMBL16103085 | 0.93 | HTR2C (0.39) | HTR2CSLC6A4HTR2ABACE1 | |
| SCHEMBL16103527 | 0.93 | HTR2C (0.39) | HTR2CSLC6A4HTR2ABACE1 | |
| SCHEMBL16099464 | 0.90 | MEN1 (0.35) | HTR2CSLC6A4ALDH1A1RAB9AHTR2A | |
| SCHEMBL16099465 | 0.90 | MEN1 (0.35) | HTR2CSLC6A4ALDH1A1RAB9AHTR2A | |
| SCHEMBL16120043 | 0.89 | HTR2C (0.41) | HTR2CSLC6A4ALDH1A1HTR2A | |
| SCHEMBL16125892 | 0.87 | HTR2C (0.39) | HTR2CSLC6A4ALDH1A1HTR2APDE4A | |
| SCHEMBL17465771 | 0.87 | HTR2C (0.39) | HTR2CSLC6A4HTR2A | |
| SCHEMBL16120040 | 0.87 | HTR2C (0.38) | HTR2CSLC6A4NPC1RAB9AHTR2A | |
| SCHEMBL16120067 | 0.86 | HTR2C (0.38) | HTR2CSLC6A4ALDH1A1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970220-A2 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153235-A2 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |