Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 3/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14979165 | 0.88 | PTGDR2 (0.54) | PTGDR2KDM4EMAPTHDAC1HDAC6 | |
| SCHEMBL16085964 | 0.85 | PTGDR2 (0.46) | PTGDR2KDM4EMAPTHDAC1HDAC6 | |
| SCHEMBL16153720 | 0.81 | PTGDR2 (0.53) | PTGDR2KDM4EMAPTHDAC1HDAC6 | |
| SCHEMBL21280222 | 0.77 | KMT2A (0.53) | PTGDR2KDM4EMAPTMEN1NPC1 | |
| SCHEMBL14979183 | 0.77 | PTGDR2 (0.52) | PTGDR2MAPTHDAC1HDAC6MEN1 | |
| SCHEMBL21280071 | 0.76 | PTGDR2 (0.56) | PTGDR2KDM4EMAPTHDAC1HDAC6 | |
| SCHEMBL14979188 | 0.76 | PTGDR2 (0.58) | PTGDR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL16153717 | 0.75 | PTGDR2 (0.54) | PTGDR2MAPTHDAC1HDAC6MEN1 | |
| SCHEMBL16085864 | 0.74 | TDP1 (0.47) | PTGDR2KDM4EMAPTHDAC1HDAC6 | |
| SCHEMBL16155841 | 0.74 | PTGDR2 (0.53) | PTGDR2HDAC1HDAC6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2781508-A1 | NITROGEN-CONTAINING FUSED RING COMPOUNDS FOR USE AS CRTH2 ANTAGONISTS | KBP Biosciences Co., Ltd. (CN) | 2014-09-24 | — | — | EP | disclosed |