Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | C5 | P01031 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787495 | 0.96 | HTT (0.58) | HTTALDH1A1KMT2APTK2BKDM4E | |
| SCHEMBL7998596 | 0.90 | HTT (0.63) | HTTALDH1A1KMT2APTK2BKDM4E | |
| SCHEMBL568543 | 0.88 | HTT (0.74) | HTTALDH1A1KMT2APTK2BKDM4E | |
| SCHEMBL29829739 | 0.88 | HTT (0.74) | HTTALDH1A1KMT2APTK2BKDM4E | |
| SCHEMBL5172254 | 0.88 | HTT (0.74) | HTTALDH1A1KMT2APTK2BKDM4E | |
| SCHEMBL4611032 | 0.87 | HTT (0.60) | HTTALDH1A1KMT2APTK2BKDM4E | |
| SCHEMBL9410810 | 0.87 | HTT (0.60) | HTTALDH1A1KMT2APTK2BKDM4E | |
| SCHEMBL9954542 | 0.87 | HTT (0.60) | HTTALDH1A1KMT2APTK2BKDM4E | |
| SCHEMBL28919783 | 0.87 | HTT (0.60) | HTTALDH1A1KMT2APTK2BKDM4E | |
| SCHEMBL8850111 | 0.87 | HTT (0.60) | HTTALDH1A1KMT2APTK2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296306-B1 | BASE-PROTECTED OLIGONUCLEOTIDE | AJINOMOTO KK (JP) | 2022-11-09 | — | — | EP | disclosed |
| EP-2816053-B1 | BASE-PROTECTED OLIGONUCLEOTIDE | AJINOMOTO KK (JP) | 2021-03-24 | — | — | EP | disclosed |
| EP-3296306-A1 | BASE-PROTECTED OLIGONUCLEOTIDE | AJINOMOTO CO., INC. (JP) | 2018-03-21 | — | — | EP | disclosed |
| EP-2816053-A1 | BASE-PROTECTED OLIGONUCLEOTIDE | Ajinomoto Co., Inc. (JP) | 2014-12-24 | — | — | EP | disclosed |
| US-8846885-B2 | Oligonucleotide with protected base | AJINOMOTO CO., INC. (JP) | 2014-09-30 | — | — | US | disclosed |