SCHEMBL16105136

SCHEMBL16105136

Cc1cc(Cc2c[nH]c(-c3nc4n(c(=O)c3O)CC3CCC4(NC(=O)C(=O)N(C)C)CC3)n2)ccc1F

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.31
CCR3 P51677 1/20 0.30
SSTR1 P30872 1/20 0.30
SSTR4 P31391 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL14122205 0.96 CYP2C9 (0.30) CYP2C9
SCHEMBL9905222 0.91 CYP2C9 (0.37) CYP2C9
SCHEMBL9905804 0.89
SCHEMBL16105097 0.88 CYP2C9 (0.31) CYP2C9
SCHEMBL9921619 0.87
SCHEMBL9905142 0.86 GRIN1 (0.31)
SCHEMBL16105113 0.85 PARP1 (0.33) CYP2C9
SCHEMBL16105096 0.85
Trifluoroacetic Acid SCHEMBL9905301 0.84 CYP2C9 (0.31) CYP2C9
SCHEMBL16105143 0.84 NTRK1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8846659-B2 HIV integrase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2014-09-30 US claimed