SCHEMBL16110562

SCHEMBL16110562

O=C(OC1CC1)C1OC12CCC2

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.33
FABP7 O15540 1/20 0.31
FABP5 Q01469 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14968328 0.96 CYP2C19 (0.36) CYP2C19FABP7FABP5ALDH1A1
SCHEMBL16109860 0.94 CYP2C19 (0.35) CYP2C19FABP7FABP5
SCHEMBL16109512 0.94 CYP2C19 (0.39) CYP2C19FABP7FABP5
SCHEMBL14967571 0.94 CYP2C19 (0.39) CYP2C19FABP7FABP5ALDH1A1
SCHEMBL14966929 0.93 CYP2C19 (0.41) CYP2C19FABP7FABP5
SCHEMBL14967881 0.91 CYP2C19 (0.42) CYP2C19FABP7FABP5
SCHEMBL14967495 0.91 CYP2C19 (0.39) CYP2C19FABP7FABP5
SCHEMBL14967426 0.89 CYP2C19 (0.41) CYP2C19FABP7FABP5ALDH1A1
SCHEMBL14967049 0.89 CYP2C19 (0.45) CYP2C19FABP7FABP5ALDH1A1
SCHEMBL14967795 0.89 CYP2C19 (0.45) CYP2C19FABP7FABP5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed