Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20150683 | 0.78 | BRD4 (0.46) | BRD4ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL21566543 | 0.72 | BRD4 (0.41) | BRD4ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL17457424 | 0.72 | BRD4 (0.41) | BRD4ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL17527341 | 0.69 | BRD4 (0.51) | BRD4ALDH1A1CYP3A4CYP2C9BRD2 | |
| SCHEMBL29920839 | 0.68 | MIF (0.61) | BRD4ALDH1A1 | |
| SCHEMBL17807864 | 0.68 | BRD4 (0.58) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL17798015 | 0.68 | MIF (0.61) | BRD4ALDH1A1 | |
| SCHEMBL17798168 | 0.68 | BRD4 (0.58) | BRD4EP300CREBBPBRD2BRD3 | |
| SCHEMBL15815509 | 0.68 | BRD4 (0.58) | BRD4ALDH1A1CYP3A4CYP2C9BRD2 | |
| SCHEMBL15815388 | 0.67 | BRD4 (0.70) | BRD4EP300CREBBPBRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968360-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF BROMODOMAIN-CONTAINING PROTEINS | ConverGene LLC (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014159837-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF BROMODOMAIN-CONTAINING PROTEINS | CONVERGENE LLC (US) | 2014-10-02 | — | — | WO | disclosed |