Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16112613 | 1.00 | NR1I2 (0.48) | NR1I2KCNH2 | |
| SCHEMBL16113895 | 0.89 | NR1I2 (0.48) | NR1I2KCNH2 | |
| SCHEMBL16112848 | 0.89 | NR1I2 (0.48) | NR1I2KCNH2 | |
| SCHEMBL16112830 | 0.84 | NR1I2 (0.47) | NR1I2KCNH2 | |
| SCHEMBL16148449 | 0.84 | NR1I2 (0.71) | NR1I2KCNH2 | |
| SCHEMBL16113746 | 0.82 | CYP3A4 (0.51) | NR1I2KCNH2 | |
| SCHEMBL16112483 | 0.81 | CYP3A4 (0.33) | NR1I2KCNH2 | |
| SCHEMBL16113333 | 0.79 | NR1I2 (0.61) | NR1I2 | |
| SCHEMBL16112770 | 0.79 | KCNH2 (0.48) | NR1I2KCNH2 | |
| SCHEMBL16113135 | 0.79 | KCNH2 (0.48) | NR1I2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970274-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | Bristol-Myers Squibb Company (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014159959-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-10-02 | — | — | WO | disclosed |