Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 3/20 | 0.58 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.50 |
| ▸ | MDM4 | O15151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31688554 | 0.99 | TLR2 (0.59) | TLR2MDM2MDM4TP53KMT2A | |
| SCHEMBL16048758 | 0.94 | TLR2 (0.51) | TLR2MDM2MDM4TP53KMT2A | |
| SCHEMBL16048760 | 0.94 | TLR2 (0.51) | TLR2MDM2MDM4TP53KMT2A | |
| SCHEMBL12254867 | 0.94 | TLR2 (0.57) | TLR2MDM2MDM4TP53KMT2A | |
| SCHEMBL31370078 | 0.93 | TLR2 (0.56) | TLR2MDM2MDM4TP53KMT2A | |
| SCHEMBL20561672 | 0.93 | TLR2 (0.52) | TLR2MDM2MDM4TP53KMT2A | |
| SCHEMBL30895488 | 0.93 | TLR2 (0.52) | TLR2MDM2MDM4TP53KMT2A | |
| SCHEMBL20561674 | 0.93 | TLR2 (0.52) | TLR2MDM2MDM4TP53KMT2A | |
| SCHEMBL32670249 | 0.93 | TLR2 (0.52) | TLR2MDM2MDM4TP53KMT2A | |
| SCHEMBL30895547 | 0.93 | TLR2 (0.52) | TLR2MDM2MDM4TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968599-A1 | LIGAND-THERAPEUTIC AGENT CONJUGATES AND SILICON-BASED LINKERS | Albany Molecular Research, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014160305-A1 | LIGAND-THERAPEUTIC AGENT CONJUGATES AND SILICON-BASED LINKERS | ALBANY MOLECULAR RESEARCH, INC. (US) | 2014-10-02 | — | — | WO | disclosed |