Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.80 |
| ▸ | SCN1A | P35498 | 2/20 | 0.56 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.56 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16119793 | 1.00 | SCN9A (0.80) | SCN9ASCN1ASCN5ASCN2ASCN8A | |
| SCHEMBL16103349 | 0.89 | SCN9A (1.00) | SCN9ASCN1ASCN5ASCN2ASCN8A | |
| SCHEMBL18400055 | 0.83 | SCN9A (0.84) | SCN9ASCN1ASCN5ASCN2ASCN8A | |
| SCHEMBL18400108 | 0.81 | SCN9A (0.76) | SCN9ASCN1ASCN5ASCN2ASCN8A | |
| SCHEMBL16119783 | 0.81 | SCN9A (1.00) | SCN9ASCN1ASCN5ASCN2ASCN8A | |
| SCHEMBL17418039 | 0.81 | SCN9A (1.00) | SCN9ASCN1ASCN5ASCN2ASCN8A | |
| SCHEMBL18400135 | 0.80 | SCN9A (0.73) | SCN9ASCN1ASCN5ASCN2ASCN8A | |
| SCHEMBL18400048 | 0.79 | SCN9A (0.64) | SCN9ASCN1ASCN5ASCN2ASCN8A | |
| SCHEMBL17433231 | 0.78 | SCN9A (0.81) | SCN9ASCN1ASCN5ASCN2ASCN8A | |
| SCHEMBL18400156 | 0.76 | SCN9A (0.72) | SCN9ASCN1ASCN5ASCN2ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014153037-A1 | SUBSTITUTED TRIAZOLOPYRIDINES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |