Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27963432 | 0.85 | GAA (0.32) | GAAGABRA1GABRB2 | |
| SCHEMBL16124337 | 0.74 | NPSR1 (0.36) | — | |
| SCHEMBL16124341 | 0.74 | ATM (0.36) | — | |
| SCHEMBL14106810 | 0.69 | ATM (0.36) | — | |
| SCHEMBL12352206 | 0.68 | GAA (0.61) | GAAMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL2612447 | 0.66 | GAA (0.48) | GAAMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL11210296 | 0.66 | GAA (0.51) | GAAMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL10479363 | 0.66 | GAA (0.39) | GAAMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL6075102 | 0.65 | GAA (0.39) | GAAMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL2612461 | 0.65 | GAA (0.66) | GAAMEN1CYP3A4MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140288641-A1 | OXIDATION RESISTANT BIOPROSTHETIC TISSUES AND PREPARATION THEREOF | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2014-09-25 | — | — | US | disclosed |