Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.38 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | FRK | P42685 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.37 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.37 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16033927 | 0.85 | KDM4C (0.41) | KDM4CKDM2BTGFBR1PHF8GRM5 | |
| SCHEMBL16034004 | 0.85 | KDM4C (0.41) | KDM4CKDM2BPHF8GRM5CTSL | |
| SCHEMBL16034598 | 0.82 | KDM4C (0.41) | KDM4CKDM2BTGFBR1TGFBR2PHF8 | |
| SCHEMBL16034550 | 0.79 | KDM4C (0.39) | KDM4CKDM2BTGFBR1PHF8GRM5 | |
| SCHEMBL16033852 | 0.78 | PHF8 (0.51) | KDM4CKDM2BPHF8GRM5KCNH2 | |
| SCHEMBL16033744 | 0.78 | KDM4C (0.41) | KDM4CKDM2BTGFBR1PHF8GRM5 | |
| SCHEMBL16034905 | 0.78 | KDM4C (0.57) | KDM4CKDM2BGRM5KCNH2NPY5R | |
| SCHEMBL16033536 | 0.75 | PHF8 (0.60) | KDM4CKDM2BPHF8GRM5MAPK14 | |
| SCHEMBL16126212 | 0.74 | KDM5A (0.43) | KDM4CKDM2BPHF8GRM5 | |
| SCHEMBL9792784 | 0.66 | NPY5R (0.45) | KDM4CGRM5KCNH2NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |