Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 18/20 | 0.68 |
| ▸ | S1PR3 | Q99500 | 18/20 | 0.68 |
| ▸ | CFTR | P13569 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16130305 | 0.94 | S1PR1 (0.68) | S1PR1S1PR3 | |
| SCHEMBL16130235 | 0.92 | S1PR1 (0.67) | S1PR1S1PR3CFTR | |
| SCHEMBL12912661 | 0.87 | S1PR1 (0.64) | S1PR1S1PR3 | |
| SCHEMBL945347 | 0.87 | S1PR1 (0.67) | S1PR1S1PR3 | |
| SCHEMBL16130298 | 0.86 | S1PR1 (0.61) | S1PR1S1PR3 | |
| SCHEMBL12912662 | 0.86 | S1PR1 (0.62) | S1PR1S1PR3 | |
| SCHEMBL16130299 | 0.86 | S1PR3 (0.71) | S1PR1S1PR3CFTR | |
| SCHEMBL16130255 | 0.85 | S1PR1 (0.51) | S1PR1S1PR3CFTRPIM1CDK5 | |
| SCHEMBL16130283 | 0.85 | S1PR3 (0.73) | S1PR1S1PR3 | |
| SCHEMBL16130302 | 0.85 | S1PR1 (0.62) | S1PR1S1PR3CFTRDYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE45174-E1 | Thiazolidin-4-one derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2014-09-30 | — | — | US | disclosed |