Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 20/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12135610 | 0.95 | PTK2 (1.00) | PTK2 | |
| SCHEMBL12135613 | 0.92 | PTK2 (1.00) | PTK2 | |
| SCHEMBL19919029 | 0.92 | PTK2 (0.90) | PTK2 | |
| SCHEMBL12135601 | 0.88 | PTK2 (1.00) | PTK2 | |
| SCHEMBL19918899 | 0.88 | PTK2 (0.89) | PTK2 | |
| SCHEMBL12135593 | 0.88 | PTK2 (1.00) | PTK2 | |
| SCHEMBL12135585 | 0.88 | PTK2 (1.00) | PTK2 | |
| SCHEMBL12135603 | 0.86 | PTK2 (1.00) | PTK2 | |
| SCHEMBL12135141 | 0.86 | PTK2 (1.00) | PTK2 | |
| SCHEMBL12135019 | 0.86 | PTK2 (1.00) | PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846689-B2 | Substituted pyrimidines for the treatment of diseases such as cancer | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-30 | — | — | US | disclosed |
| US-8846689-B2 | Substituted pyrimidines for the treatment of diseases such as cancer | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-30 | — | — | US | disclosed |