SCHEMBL16133235

SCHEMBL16133235

c1ccc2c(c1)ccc1c3cccc(-c4ccc5c(c4)c4ccccc4c4cc6c7ccccc7c7ccccc7c6cc54)c3sc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 5/20 0.47
CYP1B1 Q16678 5/20 0.47
CYP1A2 P05177 4/20 0.46
ALOX5 P09917 1/20 0.46
HPRT1 P00492 4/20 0.39
MCL1 Q07820 1/20 0.36
ACMSD Q8TDX5 1/20 0.36
LIMK1 P53667 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
S1PR4 O95977 1/20 0.34
S1PR5 Q9H228 1/20 0.34
PRKDC P78527 1/20 0.34
TDP1 Q9NUW8 2/20 0.34
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CYP2A6 P11509 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15893341 0.98 CYP1B1 (0.48) CYP1A1CYP1B1CYP1A2ALOX5HPRT1
SCHEMBL16133233 0.96 CYP1A1 (0.47) CYP1A1CYP1B1CYP1A2ALOX5HPRT1
SCHEMBL17167414 0.95 CYP1B1 (0.46) CYP1A1CYP1B1CYP1A2ALOX5HPRT1
SCHEMBL15893358 0.94 CYP1A1 (0.48) CYP1A1CYP1B1CYP1A2ALOX5HPRT1
SCHEMBL16133168 0.94 CYP1A1 (0.44) CYP1A1CYP1B1CYP1A2ALOX5HPRT1
SCHEMBL15893355 0.94 CYP1A1 (0.48) CYP1A1CYP1B1CYP1A2ALOX5HPRT1
SCHEMBL15893345 0.94 CYP1B1 (0.47) CYP1A1CYP1B1CYP1A2ALOX5HPRT1
SCHEMBL17167411 0.93 CYP1A1 (0.43) CYP1A1CYP1B1CYP1A2ALOX5S1PR4
SCHEMBL15945932 0.92 CYP1A1 (0.46) CYP1A1CYP1B1CYP1A2ALOX5HPRT1
SCHEMBL17167423 0.92 CYP1A1 (0.46) CYP1A1CYP1B1CYP1A2ALOX5HPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed