Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 5/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670262 | 0.85 | HTR2C (0.56) | HTR2CHTR6HTR1ASLC6A2SLC6A4 | |
| SCHEMBL2781842 | 0.83 | HTR2C (0.47) | HTR2CPARP1HTR6HTR1ASLC6A2 | |
| SCHEMBL27605525 | 0.80 | NOTUM (0.45) | NOTUM | |
| SCHEMBL17323546 | 0.78 | HTR2C (0.51) | HTR2CHTR6HTR1ASLC6A2SLC6A4 | |
| SCHEMBL25422738 | 0.76 | PARP1 (0.47) | HTR2CPARP1HTR1ASLC6A2SLC6A4 | |
| Acetamide SCHEMBL27654523 | 0.76 | HTR2C (0.58) | HTR2CPARP1HTR6HTR1ASLC6A2 | |
| SCHEMBL21145876 | 0.76 | PARP1 (0.42) | HTR2CPARP1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13646083 | 0.75 | HTR2C (0.61) | HTR2CHTR6NOTUM | |
| SCHEMBL28086725 | 0.75 | HTR2C (0.59) | HTR2CHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3809376 | 0.74 | HTR2C (0.59) | HTR2CPARP1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029547-B1 | Synthesis of 4-aryl 4-acyl piperidine, its salts and analogs using indium metal | SAMI LABS LIMITED (IN) | 2015-05-12 | — | — | US | disclosed |
| US-8853407-B1 | Synthesis of 4-aryl 4-acyl piperidine, its salts and analogs using indium metal | SAMI LABS LIMITED (IN) | 2014-10-07 | — | — | US | disclosed |