SCHEMBL1613820

SCHEMBL1613820

CN(C)C(N(C)C)C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3926726 0.73
SCHEMBL3926728 0.71 MAPT (0.39)
SCHEMBL2101989 0.69
SCHEMBL19968205 0.67
SCHEMBL13623711 0.64
SCHEMBL22219448 0.64
SCHEMBL1833058 0.64
SCHEMBL24079338 0.62
SCHEMBL7056257 0.62
Iodide SCHEMBL3387682 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066296-A1 METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF ALEXION PHARMACEUTICALS, INC. (US) 2025-02-27 US disclosed
EP-4448490-A2 METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF Alexion Pharmaceuticals, Inc. (US) 2024-10-23 EP disclosed
CN-118382616-A Synthesis method of complement factor D inhibitor and intermediate thereof 阿雷克森制药公司 2024-07-23 CN disclosed
WO-2023114200-A2 METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF ALEXION PHARMACEUTICALS, INC. (US) 2023-06-22 WO disclosed
US-10801105-B2 Process for the generation of thin inorganic films BASF SE (DE) 2020-10-13 US disclosed
EP-2315751-A1 ALKYNYL ALCOHOLS AS KINASE INHIBITORS Amgen Inc. (US) 2011-05-04 EP disclosed
US-20110086834-A1 ALKYNYL ALCOHOLS AS KINASE INHIBITORS AMGEN INC. (US) 2011-04-14 US disclosed
EP-1423380-B1 PYRAZOLE-DERIVED KINASE INHIBITORS AND USES THEREOF VERTEX PHARMA (US) 2010-12-15 EP disclosed
WO-2009158011-A1 ALKYNYL ALCOHOLS AS KINASE INHIBITORS AMGEN INC. (US) 2009-12-30 WO disclosed
EP-1423382-B1 PYRAZOLE-DERIVED KINASE INHIBITORS AND USES THEREOF VERTEX PHARMA (US) 2008-04-16 EP disclosed
US-6525059-B1 Mitogen-activated protein kinases (MAP); G. D. SEARLE & COMPANY 2003-02-25 US disclosed
US-6514977-B1 For treating p38 kinase mediated disorders G.D. SEARLE & COMPANY 2003-02-04 US disclosed
US-6423713-B1 Substituted pyrazoles as p38 kinase inhibitors G. D. SEARLE & COMPANY 2002-07-23 US disclosed
US-6306883-B1 NOVEL PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING A COMPOUND AND INHIBITING CYTOKINES BY A COMPOUND OF FORMULA (I) AND THE TREATMENT OF CYTOKINES MEDIATED DISEASES, SMITHKLINE BEECHAM CORPORATION 2001-10-23 US disclosed
US-5998425-A CYTOKINE ANTAGONIST; ANTIARTHRITIC AGENT SMITHKLINE BEECHAM CORPORATION (US) 1999-12-07 US disclosed
EP-0871622-A4 1998-10-21 EP disclosed
EP-0871622-A1 NOVEL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 1998-10-21 EP disclosed
WO-1995031451-A1 NOVEL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 1995-11-23 WO disclosed
US-4341720-A FROM AN OXALIC ACID COMPOUND AND PHOSPHORUS PENTACHLORIDE IN PRESENCE OF A TERTIARY AMINE COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1982-07-27 US disclosed
EP-0009658-A1 Process for the preparation of oxalyl chloride BAYER AG (DE) 1980-04-16 EP disclosed