SCHEMBL16140

SCHEMBL16140

NNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.61
MEN1 O00255 6/20 0.61
KMT2A Q03164 6/20 0.61
MAPK1 P28482 5/20 0.61
TDP1 Q9NUW8 4/20 0.60
TXNRD1 Q16881 1/20 0.56
TXNRD3 Q86VQ6 1/20 0.56
TXNRD2 Q9NNW7 1/20 0.56
ALDH1A1 P00352 4/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
GPR35 Q9HC97 2/20 0.53
TP53 P04637 1/20 0.53
HPGD P15428 1/20 0.53
TSHR P16473 1/20 0.53
HIF1A Q16665 1/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
CTDSP1 Q9GZU7 1/20 0.53
CRHBP P24387 1/20 0.53
CRHR2 Q13324 1/20 0.53
POLB P06746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29352891 1.00 MAPT (0.61) MAPTMEN1KMT2AMAPK1TDP1
SCHEMBL27470180 1.00 MAPT (0.61) MAPTMEN1KMT2AMAPK1TDP1
SCHEMBL28247841 1.00 MAPT (0.61) MAPTMEN1KMT2AMAPK1TDP1
Methane SCHEMBL28068825 0.98 MAPT (0.59) MAPTMEN1KMT2AMAPK1TDP1
Water SCHEMBL9233283 0.98 MAPT (0.59) MAPTMEN1KMT2AMAPK1TDP1
Hydrochloric Acid SCHEMBL1665136 0.98 MAPT (0.59) MAPTMEN1KMT2AMAPK1TDP1
Hydrochloric Acid SCHEMBL11150669 0.98 MAPT (0.59) MAPTMEN1KMT2AMAPK1TDP1
Formaldehyde SCHEMBL28414752 0.96 MAPT (0.58) MAPTMEN1KMT2AMAPK1TDP1
Methyl Alcohol SCHEMBL27980452 0.95 MAPT (0.56) MAPTMEN1KMT2AMAPK1TDP1
Phosphoric Acid SCHEMBL30231818 0.92 MAPT (0.54) MAPTMEN1KMT2AMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7155 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622925-B2 Edible enterosorbents used to mitigate acute exposures to ingestible environmental toxins following outbreaks, natural disasters and emergencies NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2026-05-12 US claimed
US-12564565-B2 Stable pharmaceutical formulations of amino acids, peptides or proteins IBSA INSTITUT BIOCHIMIQUE SA (CH) 2026-03-03 US claimed
US-20250381159-A1 STABLE PHARMACEUTICAL FORMULATIONS OF AMINO ACIDS, PEPTIDES OR PROTEINS ALTERGON SA (CH) 2025-12-18 US claimed
EP-3315968-B1 UNIVERSAL ANTIGEN RETRIEVAL COMPOUNDS AND METHODS OF USE UNIV HOUSTON SYSTEM (US) 2025-10-15 EP claimed
US-20250164433-A1 SYSTEMS AND METHODS FOR POINT-OF-NEED SENSING USING AN ELECTROCHEMICAL SENSOR E-Sentience, Inc. 2025-05-22 US claimed
WO-2025090061-A1 ULTRASONIC INDICATOR DEVICE AND METHOD FOR MONITORING ULTRASONICATION JP LABORATORIES, INC. (US) 2025-05-01 WO claimed
US-20250136550-A1 PROCESSES FOR PREPARING REVEFENACIN AND COMPOSITIONS COMPRISING THE SAME THERAVANCE BIOPHARMA R&D IP, LLC 2025-05-01 US claimed
US-20250129002-A1 PRODUCTION METHOD OF PRODUCT 1,3-BUTYLENE GLYCOL KH NEOCHEM CO., LTD. (JP) 2025-04-24 US claimed
US-12265073-B2 Method and system for chromogenic array-based food testing UNIVERSITY OF MASSACHUSETTS (US) 2025-04-01 US claimed
WO-2025000223-A1 NON-TARGETED MASS SPECTROMETRY IDENTIFICATION METHOD FOR TOBACCO CARBONYL COMPONENTS 云南中烟工业有限责任公司 2025-01-02 WO claimed
US-4212938-A Reagent and method for the determination of cholesterol BOEHRINGER MANNHEIM GMBH (DE) 1980-07-15 US claimed
US-4202886-A ANTITUMOR AGENTS MEIJI SEIKA KAISHA, LTD. (JP) 1980-05-13 US claimed
US-4181575-A Composition and method for the determination of cholesterol BOEHRINGER MANNHEIM GMBH (DE) 1980-01-01 US claimed
US-4167630-A Process for epimerizing beta-lactam antibiotic compounds, and related products MERCK & CO., INC. (US) 1979-09-11 US claimed
US-4151043-A Enzyme determination method SIGMA CHEMICAL COMPANY (US) 1979-04-24 US claimed
EP-0001019-A1 Phenylhydrazones, their use in insecticidal compositions and methods for their preparation COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1979-03-07 EP claimed
US-4051132-A Process for epimerizing beta-lactam antibiotic compounds by means of an acid quench MERCK & CO., INC. (US) 1977-09-27 US claimed
US-4005076-A ANTIBIOTICS GRUPPO LEPETIT S.P.A. (IT) 1977-01-25 US claimed
US-3987234-A ACRYLIC ESTER POLYMERS HENKEL & CIE G.M.B.H. (DT) 1976-10-19 US claimed
US-3969413-A Hydroformylation process using catalyst comprising cobalt and polynitroaryl compounds UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-07-13 US claimed