SCHEMBL1614248

SCHEMBL1614248

O=C(C=C/C=C/c1ccccc1)c1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 9/20 0.74
CYP1B1 Q16678 6/20 0.74
MAPT P10636 4/20 0.74
PLIN1 O60240 1/20 0.74
LMNA P02545 1/20 0.74
BCHE P06276 1/20 0.74
TNFRSF1A P19438 1/20 0.74
ACHE P22303 1/20 0.74
RECQL P46063 1/20 0.74
PLIN5 Q00G26 1/20 0.74
ABHD5 Q8WTS1 1/20 0.74
HDAC3 O15379 3/20 0.61
HDAC4 P56524 3/20 0.61
HDAC1 Q13547 3/20 0.61
HDAC7 Q8WUI4 3/20 0.61
HDAC2 Q92769 3/20 0.61
HDAC10 Q969S8 3/20 0.61
HDAC11 Q96DB2 3/20 0.61
HDAC8 Q9BY41 3/20 0.61
HDAC6 Q9UBN7 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1614247 1.00 MAOB (0.74) MAOBCYP1B1MAPTPLIN1LMNA
SCHEMBL1614246 1.00 MAOB (0.74) MAOBCYP1B1MAPTPLIN1LMNA
Bromide SCHEMBL11333938 0.98 MAOB (0.71) MAOBCYP1B1MAPTPLIN1LMNA
Bromide SCHEMBL11319714 0.98 MAOB (0.71) MAOBCYP1B1MAPTPLIN1LMNA
Bromide SCHEMBL11322338 0.98 MAOB (0.71) MAOBCYP1B1MAPTPLIN1LMNA
SCHEMBL14911041 0.93 MAOB (0.65) MAOBCYP1B1MAPTPLIN1LMNA
SCHEMBL11470657 0.91 CYP1B1 (0.61) MAOBCYP1B1MAPTPLIN1LMNA
SCHEMBL11470658 0.91 CYP1B1 (0.61) MAOBCYP1B1MAPTPLIN1LMNA
SCHEMBL14911042 0.90 MAOB (0.61) MAOBCYP1B1MAPTPLIN1LMNA
SCHEMBL2745057 0.89 CYP1B1 (0.59) MAOBCYP1B1MAPTPLIN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57010135-A None JP disclosed
CN-105998630-A Traditional Chinese medicine preparation for regulating qi and blood circulation, preparation method and special device 艾尼·图尔荪 2016-10-12 CN disclosed
US-20130017582-A1 ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON HOLDINGS, LLC (US) 2013-01-17 US disclosed
US-8338143-B2 Enhanced production of paclitaxel and taxanes by cell cultures of Taxus species PHYTON HOLDINGS, LLC (US) 2012-12-25 US disclosed
US-20110086397-A1 ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON HOLDINGS, LLC (US) 2011-04-14 US disclosed
US-20080108115-A1 ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES DFB BIOTECH, INCORPORATED (US) 2008-05-08 US disclosed
US-7264951-B1 Enhanced production of taxol and taxanes by cell cultures of Taxus species PHYTON, INC. (US) 2007-09-04 US disclosed
EP-0954596-B1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON INC (US) 2006-01-04 EP disclosed
US-20050221456-A1 Use of indanoyl amide to stimulate secondary metabolism in Taxus sp. PHYTON BIOTECH, INC. (US) 2005-10-06 US disclosed
EP-1538214-A1 Enhanced production of taxanes by cell cultures of taxus species PHYTON, INC. (US) 2005-06-08 EP disclosed
EP-1398384-A1 Enhanced production of taxanes by cell cultures of taxus species Phyton Inc. (US) 2004-03-17 EP disclosed
JP-S5710135-A PHASE TYPE OPTICAL RECORDING MATERIAL AND PHASE TYPE OPTICAL RECORDING BODY TEIJIN LTD 1982-01-19 JP disclosed