Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.72 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.67 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16143804 | 0.85 | S1PR1 (0.76) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1601115 | 0.84 | S1PR1 (1.00) | S1PR1S1PR3S1PR5KCNH2 | |
| SCHEMBL12269274 | 0.81 | S1PR1 (1.00) | S1PR1S1PR3S1PR5 | |
| SCHEMBL12269257 | 0.81 | S1PR1 (0.82) | S1PR1S1PR3S1PR5KCNH2 | |
| SCHEMBL1601425 | 0.80 | S1PR1 (1.00) | S1PR1S1PR3S1PR5KCNH2 | |
| SCHEMBL1602800 | 0.80 | S1PR1 (1.00) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1602529 | 0.80 | S1PR1 (1.00) | S1PR1S1PR3S1PR5KCNH2 | |
| SCHEMBL1602648 | 0.79 | S1PR1 (1.00) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1602782 | 0.79 | S1PR1 (0.77) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2409793 | 0.75 | S1PR1 (0.89) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364976-B1 | S1P receptor modulating compounds and use thereof | EPIX PHARM INC (US) | 2014-10-08 | — | — | EP | disclosed |