Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 19/20 | 0.53 |
| ▸ | SCN1A | P35498 | 1/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL937029 | 0.88 | SCN5A (0.65) | SCN5ASCN1ASCN2ACYP1A2MET | |
| SCHEMBL937623 | 0.79 | SCN5A (0.63) | SCN5ASCN1ASCN2ACYP1A2 | |
| SCHEMBL936953 | 0.78 | SCN5A (0.65) | SCN5ASCN1ASCN2ACYP1A2 | |
| SCHEMBL936888 | 0.78 | SCN5A (0.58) | SCN5ASCN1ASCN2ACYP1A2 | |
| SCHEMBL937167 | 0.78 | SCN5A (0.61) | SCN5ASCN1ASCN2ACYP1A2 | |
| SCHEMBL936339 | 0.78 | SCN5A (0.55) | SCN5ASCN1ASCN2ACYP1A2 | |
| SCHEMBL936416 | 0.77 | SCN5A (0.55) | SCN5ASCN1ASCN2ACYP1A2MET | |
| SCHEMBL936447 | 0.77 | SCN5A (0.54) | SCN5ASCN1ASCN2ACYP1A2MET | |
| SCHEMBL938479 | 0.76 | SCN5A (0.53) | SCN5ASCN1ASCN2A | |
| SCHEMBL939173 | 0.76 | SCN5A (0.53) | SCN5ASCN1ASCN2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371329-B2 | Fused heterocyclic compounds as ion channel modulators | GILEAD SCIENCES, INC. (US) | 2016-06-21 | — | — | US | disclosed |
| US-20140303158-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD SCIENCES, INC. (US) | 2014-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303158-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | KCNJ2, KCNH2, KCNA3 | SCN5A 52/4885SCN1A 55/4885SCN2A 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.