Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.73 |
| ▸ | PPARA | Q07869 | 14/20 | 0.73 |
| ▸ | PPARG | P37231 | 9/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16147339 | 0.89 | PPARD (0.71) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL21947717 | 0.88 | PPARD (0.68) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL24238918 | 0.87 | PPARD (0.67) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL21946955 | 0.87 | PPARD (0.69) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL21947712 | 0.86 | PPARD (0.66) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL20482074 | 0.86 | PPARD (0.78) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL3805779 | 0.85 | PPARD (0.71) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL29376887 | 0.84 | PPARD (1.00) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL29422488 | 0.84 | PPARD (1.00) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL2064674 | 0.84 | PPARD (1.00) | PPARDPPARAPPARGMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981522-A1 | PPAR AGONISTS | Salk Institute for Biological Studies (US) | 2016-02-10 | — | — | EP | disclosed |
| WO-2014165827-A1 | PPAR AGONISTS | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2014-10-09 | — | — | WO | disclosed |