⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3029183 | 0.78 | — | — | |
| SCHEMBL1858349 | 0.78 | — | — | |
| SCHEMBL6006390 | 0.72 | — | — | |
| SCHEMBL12640985 | 0.69 | — | — | |
| SCHEMBL25179 | 0.69 | — | — | |
| SCHEMBL105724 | 0.67 | — | — | |
| SCHEMBL2702508 | 0.67 | — | — | |
| SCHEMBL271372 | 0.67 | — | — | |
| SCHEMBL17887362 | 0.67 | — | — | |
| SCHEMBL28031456 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10105447-B2 | Method of treating obesity in a companion animal comprising administering a modified canine leptin polypeptide | ELANCO US INC. (US) | 2018-10-23 | — | — | US | claimed |
| EP-2970424-B1 | MODIFIED CANINE LEPTIN POLYPEPTIDES | LILLY CO ELI (US) | 2017-06-21 | — | — | EP | claimed |
| EP-2970424-A2 | MODIFIED CANINE LEPTIN POLYPEPTIDES | Eli Lilly and Company (US) | 2016-01-20 | — | — | EP | claimed |
| US-20150366983-A1 | MODIFIED CANINE LEPTIN POLYPEPTIDES | ELANCO US INC. | 2015-12-24 | — | — | US | claimed |
| WO-2014165189-A2 | MODIFIED CANINE LEPTIN POLYPEPTIDES | ELI LILLY AND COMPANY (US) | 2014-10-09 | — | — | WO | claimed |
| US-20190201491-A1 | BOVINE FIBROBLAST GROWTH FACTOR 21 AND KETOSIS IN DAIRY CATTLE | ELANCO US INC. (US) | 2019-07-04 | — | — | US | disclosed |
| US-10105447-B2 | Method of treating obesity in a companion animal comprising administering a modified canine leptin polypeptide | ELANCO US INC. (US) | 2018-10-23 | — | — | US | disclosed |
| EP-2970424-B1 | MODIFIED CANINE LEPTIN POLYPEPTIDES | LILLY CO ELI (US) | 2017-06-21 | — | — | EP | disclosed |
| US-20150366983-A1 | MODIFIED CANINE LEPTIN POLYPEPTIDES | ELANCO US INC. | 2015-12-24 | — | — | US | disclosed |