Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.67 |
| ▸ | SULT1A1 | P50225 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423269 | 0.86 | APP (0.81) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL25028302 | 0.84 | APP (0.68) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL6807683 | 0.82 | APP (0.67) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL24332359 | 0.82 | APP (0.78) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL24038224 | 0.81 | APP (0.72) | APPSULT1A1MAPTKDM4ENPC1 | |
| SCHEMBL24332463 | 0.81 | APP (0.72) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL2036269 | 0.80 | APP (1.00) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL9238817 | 0.80 | APP (1.00) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL1572293 | 0.80 | APP (0.72) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL2922465 | 0.80 | APP (0.72) | APPSULT1A1MAPTTP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981527-B1 | DERIVATIVES OF LUCIFERIN. | UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2018-10-31 | — | — | EP | disclosed |
| EP-2981527-A1 | DERIVATIVES OF LUCIFERIN | UCL Business Plc. (GB) | 2016-02-10 | — | — | EP | disclosed |
| WO-2014162157-A1 | DERIVATIVES OF LUCIFERIN | UCL BUSINESS PLC (GB) | 2014-10-09 | — | — | WO | disclosed |
| WO-2014162157-A1 | DERIVATIVES OF LUCIFERIN | UCL BUSINESS PLC (GB) | 2014-10-09 | — | — | WO | disclosed |