⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187313 | 0.74 | — | — | |
| SCHEMBL15918329 | 0.72 | — | — | |
| SCHEMBL14749799 | 0.71 | — | — | |
| SCHEMBL16139617 | 0.71 | — | — | |
| SCHEMBL23343801 | 0.70 | — | — | |
| SCHEMBL1707434 | 0.70 | — | — | |
| SCHEMBL1559274 | 0.70 | — | — | |
| SCHEMBL187229 | 0.70 | — | — | |
| SCHEMBL1559273 | 0.70 | — | — | |
| SCHEMBL24315889 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664938-A | Benzopyrimidine-containing SYK inhibitor | KBP BIOSCIENCES CO LTD | 2014-03-26 | — | — | CN | claimed |
| EP-2970099-A1 | SUBSTITUTED 3-PHENYLPROPYLAMINE DERIVATIVES FOR THE TREATMENT OF OPHTHALMIC DISEASES AND DISORDERS | Acucela, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014164905-A1 | SUBSTITUTED 3-PHENYLPROPYLAMINE DERIVATIVES FOR THE TREATMENT OF OPHTHALMIC DISEASES AND DISORDERS | ACUCELA INC. (US) | 2014-10-09 | — | — | WO | disclosed |
| CN-103664938-A | Benzopyrimidine-containing SYK inhibitor | KBP BIOSCIENCES CO LTD | 2014-03-26 | — | — | CN | disclosed |