Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10314891 | 0.88 | GRM5 (0.52) | GRM5GRM3 | |
| SCHEMBL10314930 | 0.88 | GRM5 (0.59) | GRM5GRM3 | |
| SCHEMBL10008519 | 0.87 | GRM5 (0.55) | GRM5 | |
| SCHEMBL16151982 | 0.86 | GRM5 (0.46) | GRM5 | |
| SCHEMBL10314928 | 0.85 | GRM5 (0.60) | GRM5 | |
| SCHEMBL10314877 | 0.84 | GRM5 (0.48) | GRM5GRM3 | |
| SCHEMBL10314895 | 0.84 | GRM5 (0.50) | GRM5GRM3 | |
| SCHEMBL10314892 | 0.83 | GRM5 (0.48) | GRM5 | |
| SCHEMBL10314880 | 0.82 | GRM5 (0.42) | GRM5 | |
| SCHEMBL10314881 | 0.79 | GRM5 (0.49) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853237-B2 | Naphthyridinone analogs as mGluR5 positive allosteric modulators | VANDERBILT UNIVERSITY (US) | 2014-10-07 | — | — | US | disclosed |