Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16152076 | 0.93 | GCK (0.41) | GCK | |
| SCHEMBL16152080 | 0.89 | GCK (0.43) | GCK | |
| SCHEMBL16152081 | 0.88 | GCK (0.37) | GCK | |
| SCHEMBL16152079 | 0.87 | GCK (0.54) | GCK | |
| SCHEMBL16152066 | 0.87 | GCK (0.45) | GCK | |
| SCHEMBL16152068 | 0.86 | GCK (0.42) | GCK | |
| SCHEMBL15202915 | 0.84 | GCK (0.52) | GCK | |
| SCHEMBL2658178 | 0.84 | GCK (0.52) | GCK | |
| SCHEMBL16152070 | 0.83 | SCN9A (0.33) | GCK | |
| SCHEMBL10297595 | 0.83 | GCK (0.51) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853409-B2 | Pyridin-2yl-amino-1, 2, 4-thiadiazole derivatives as glucokinase activators for the treatment of diabetes mellitus | ARRAY BIOPHARMA INC. (US) | 2014-10-07 | — | — | US | disclosed |