SCHEMBL16158264

SCHEMBL16158264

c1ccc(-c2ccc(-c3cccc(N(c4ccccc4)c4ccc5c(c4)C(c4ccccc4)(c4ccccc4)c4ccccc4-5)c3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 16/20 0.40
MEN1 O00255 2/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
KMT2A Q03164 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 1/20 0.37
OPRK1 P41145 1/20 0.37
APAF1 O14727 1/20 0.33
NPC1 O15118 1/20 0.33
THRB P10828 1/20 0.33
XBP1 P17861 1/20 0.33
PTBP1 P26599 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
GALK1 P51570 1/20 0.33
BLM P54132 1/20 0.33
SMAD3 P84022 1/20 0.33
ATM Q13315 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21010903 1.00 PDK2 (0.40) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL16158400 1.00 PDK2 (0.40) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL16158362 1.00 PDK2 (0.40) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL15290146 1.00 PDK2 (0.40) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL16158278 1.00 PDK2 (0.40) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL16158365 1.00 PDK2 (0.40) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL16922915 0.99 PDK2 (0.39) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL17903062 0.99 MEN1 (0.40) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL24622286 0.99 MAPT (0.38) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL16158333 0.99 PDK2 (0.40) PDK2MEN1LMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014163228-A1 NOVEL ORGANIC ELECTROLUMINESCENT ELEMENT COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME (주)피엔에이치테크 (KR) 2014-10-09 WO disclosed