Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | DRD4 | P21917 | 5/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16158588 | 0.90 | ABCB1 (0.42) | SMOPTGER2ABCB1CA2CA9 | |
| SCHEMBL17531438 | 0.85 | FGFR1 (0.49) | PTGER2FGFR1SRCRAB9A | |
| SCHEMBL16147263 | 0.85 | FGFR1 (0.49) | PTGER2FGFR1SRCRAB9A | |
| SCHEMBL17531469 | 0.78 | FGFR1 (0.42) | PTGER2FGFR1SRC | |
| SCHEMBL16148304 | 0.78 | FGFR1 (0.42) | PTGER2FGFR1SRC | |
| SCHEMBL16147266 | 0.75 | KMT2A (0.45) | MAPK14ALDH1A1LMNAHPGDNPC1 | |
| SCHEMBL16147349 | 0.74 | FGFR1 (0.49) | PTGER2FGFR1SRCCA2CA9 | |
| SCHEMBL17531428 | 0.74 | FGFR1 (0.49) | PTGER2FGFR1SRCCA2CA9 | |
| SCHEMBL17531440 | 0.72 | FGFR1 (0.45) | PTGER2FGFR1SRCCA2CA9 | |
| SCHEMBL16158445 | 0.72 | HCRTR1 (0.38) | PTGER2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014165815-A2 | NONSTEROIDAL AND STEROIDAL COMPOUNDS WITH POTENT ANDROGEN RECEPTOR DOWN-REGULATION AND ANTI PROSTATE CANCER ACTIVITY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2014-10-09 | — | — | WO | disclosed |