SCHEMBL16158754

SCHEMBL16158754

c1ccc(-c2cc(-c3ccc(-c4c(-c5ccc(-c6cc(-c7ccccc7)nc(-c7ccccc7)n6)cc5)c5ccccc5c5ccccc45)cc3)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 11/20 0.61
KMT2A Q03164 11/20 0.61
MAPT P10636 9/20 0.61
ALDH1A1 P00352 8/20 0.61
HPGD P15428 8/20 0.61
NTSR1 P30989 1/20 0.61
ADORA2A P29274 2/20 0.53
ADORA1 P30542 2/20 0.53
KDM4E B2RXH2 5/20 0.53
LMNA P02545 2/20 0.53
GLA P06280 1/20 0.53
NPSR1 Q6W5P4 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
CYP2C19 P33261 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
TDP1 Q9NUW8 2/20 0.47
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16158695 1.00 MEN1 (0.61) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL24264021 0.98 MEN1 (0.65) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL20405349 0.95 MEN1 (0.61) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL20404962 0.95 MEN1 (0.61) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL24527267 0.94 MEN1 (0.63) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL14079806 0.94 MEN1 (0.63) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL14079804 0.94 MEN1 (0.63) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL21416113 0.93 MEN1 (0.54) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL21416110 0.93 MEN1 (0.54) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL20405237 0.93 MEN1 (0.59) MEN1KMT2AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2873666-B1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT CONTAINING SAME LG CHEMICAL LTD (KR) 2017-09-20 EP disclosed
US-9412954-B2 Heterocyclic compound and organic electronic element containing same LG CHEM, LTD. (KR) 2016-08-09 US disclosed
US-9412954-B2 Heterocyclic compound and organic electronic element containing same LG CHEM, LTD. (KR) 2016-08-09 US disclosed
EP-2873666-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT CONTAINING SAME LG Chem, Ltd. (KR) 2015-05-20 EP disclosed
US-20140299192-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT CONTAINING SAME LG CHEM, LTD. (KR) 2014-10-09 US disclosed
US-20140299192-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT CONTAINING SAME LG CHEM, LTD. (KR) 2014-10-09 US disclosed