SCHEMBL16159449

SCHEMBL16159449

C1=COC(c2cccc(-c3c4ccccc4c(-c4cccc(-c5ncco5)c4)c4ccc(-c5ccc(-c6cccc7ccccc67)cc5)cc34)c2)N1

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALK Q9UM73 1/20 0.32
CCNC P24863 1/20 0.32
CDK8 P49336 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
S1PR1 P21453 1/20 0.31
S1PR3 Q99500 1/20 0.31
HDAC4 P56524 1/20 0.31
MCL1 Q07820 1/20 0.30
ENPP3 O14638 1/20 0.30
ENPP1 P22413 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16159486 0.97 S1PR1 (0.32) S1PR1S1PR3HDAC4
SCHEMBL16159474 0.92 HDAC4 (0.36) HDAC4MCL1
SCHEMBL16159461 0.92 HDAC4 (0.36) HDAC4MCL1
SCHEMBL16159446 0.92 HDAC4 (0.36) HDAC4MCL1
SCHEMBL16159464 0.91 HDAC4 (0.34) HDAC4
SCHEMBL16159463 0.91 HDAC4 (0.35) HDAC4MCL1
SCHEMBL16159526 0.91 HDAC4 (0.32) HDAC4
SCHEMBL16159587 0.89 CCNC (0.34) ALKCCNCCDK8MCL1
SCHEMBL16159318 0.88 HDAC4 (0.33) HDAC4
SCHEMBL16159485 0.88 ENPP1 (0.31) ALKCCNCCDK8ENPP3ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014163173-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME JNC株式会社 (JP) 2014-10-09 WO disclosed