Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.53 |
| ▸ | DPP4 | P27487 | 13/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.33 |
| ▸ | FAP | Q12884 | 5/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.33 |
| ▸ | PREP | P48147 | 3/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.33 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23408415 | 1.00 | PIK3CD (0.53) | PIK3CDDPP4CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL24827448 | 1.00 | PIK3CD (0.53) | PIK3CDDPP4CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL13252946 | 0.88 | PIK3CD (0.50) | PIK3CDDPP4DPP7FAPDPP8 | |
| SCHEMBL25099271 | 0.88 | PIK3CD (0.50) | PIK3CDDPP4DPP7FAPDPP8 | |
| SCHEMBL17471258 | 0.86 | PIK3CD (0.49) | PIK3CDDPP4DPP7FAPDPP8 | |
| SCHEMBL23408433 | 0.86 | PIK3CD (0.49) | PIK3CDDPP4DPP7FAPDPP8 | |
| SCHEMBL25099273 | 0.76 | PIK3CD (0.51) | PIK3CDCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL25099105 | 0.76 | PIK3CD (0.51) | PIK3CDCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL25099107 | 0.76 | PIK3CD (0.51) | PIK3CDCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL17323643 | 0.76 | PIK3CD (0.41) | PIK3CDDPP4CHRNB2CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021102322-A1 | CELL-PERMEABLE CYCLIC PEPTIDES AND USES THEREOF | UNNATURAL PRODUCTS INC. (US) | 2021-05-27 | — | — | WO | disclosed |
| US-20180170857-A1 | PPAR AGONISTS | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2018-06-21 | — | — | US | disclosed |
| US-9938234-B2 | PPAR agonists | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2018-04-10 | — | — | US | disclosed |
| US-9938234-B2 | PPAR agonists | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2018-04-10 | — | — | US | disclosed |
| US-20160023991-A1 | PPAR AGONISTS | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160023991-A1 | PPAR AGONISTS | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2016-01-28 | — | — | US | disclosed |
| WO-2014165827-A1 | PPAR AGONISTS | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2014-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180170857-A1 | PPAR AGONISTS | PPARG, PPARD, PPARA | PIK3CD 614/4885DPP4 743/4885CHRNB2 407/4885 |
| US-20160023991-A1 | PPAR AGONISTS | PPARG, PPARD, PPARA | PIK3CD 614/4885DPP4 743/4885CHRNB2 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.