Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16162132 | 0.90 | RPS6KB1 (0.82) | RPS6KB1AURKA | |
| SCHEMBL665191 | 0.89 | RPS6KB1 (1.00) | RPS6KB1AURKA | |
| SCHEMBL16162052 | 0.82 | RPS6KB1 (0.79) | RPS6KB1AURKA | |
| SCHEMBL664843 | 0.81 | RPS6KB1 (1.00) | RPS6KB1AURKA | |
| SCHEMBL664534 | 0.80 | AURKA (1.00) | RPS6KB1AURKA | |
| SCHEMBL666327 | 0.80 | RPS6KB1 (1.00) | RPS6KB1AURKA | |
| SCHEMBL666984 | 0.80 | AURKA (0.91) | RPS6KB1AURKA | |
| SCHEMBL666147 | 0.80 | AURKA (1.00) | RPS6KB1AURKA | |
| SCHEMBL667000 | 0.79 | RPS6KB1 (1.00) | RPS6KB1AURKA | |
| SCHEMBL16162150 | 0.79 | AURKA (0.78) | RPS6KB1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396307-B1 | NOVEL AMINO AZAHETEROCYCLIC CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2014-10-15 | — | — | EP | claimed |