Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 20/20 | 0.67 |
| ▸ | AURKA | O14965 | 15/20 | 0.67 |
| ▸ | AKT1 | P31749 | 3/20 | 0.67 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.67 |
| ▸ | INCENP | Q9NQS7 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16161918 | 0.90 | RPS6KB1 (0.76) | RPS6KB1AURKAAKT1AURKBINCENP | |
| SCHEMBL16162052 | 0.89 | RPS6KB1 (0.79) | RPS6KB1AURKAAKT1AURKBINCENP | |
| SCHEMBL665473 | 0.87 | RPS6KB1 (0.81) | RPS6KB1AURKAAKT1AURKBINCENP | |
| SCHEMBL16161882 | 0.84 | RPS6KB1 (0.76) | RPS6KB1AURKAAKT1AURKBINCENP | |
| SCHEMBL16161913 | 0.84 | RPS6KB1 (0.79) | RPS6KB1AURKA | |
| SCHEMBL16162124 | 0.81 | RPS6KB1 (0.81) | RPS6KB1AURKAAKT1AURKBINCENP | |
| SCHEMBL16162047 | 0.80 | RPS6KB1 (0.75) | RPS6KB1AURKAAKT1AURKBINCENP | |
| SCHEMBL665990 | 0.80 | RPS6KB1 (1.00) | RPS6KB1AURKAAKT1AURKBINCENP | |
| SCHEMBL663752 | 0.80 | RPS6KB1 (1.00) | RPS6KB1AURKAAKT1AURKBINCENP | |
| SCHEMBL16162090 | 0.80 | RPS6KB1 (0.76) | RPS6KB1AURKAAKT1AURKBINCENP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396307-B1 | NOVEL AMINO AZAHETEROCYCLIC CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2014-10-15 | — | — | EP | claimed |