Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11887806 | 0.84 | APEX1 (0.64) | NPSR1APEX1TOP2AKDM4ERECQL | |
| SCHEMBL4785390 | 0.83 | NPSR1 (0.75) | NPSR1APEX1TOP2AKDM4ERECQL | |
| SCHEMBL29424865 | 0.82 | NPSR1 (0.56) | NPSR1APEX1TOP2AKDM4ERECQL | |
| SCHEMBL6092621 | 0.82 | KDM4E (0.68) | NPSR1APEX1TOP2AKDM4ERECQL | |
| SCHEMBL2996556 | 0.82 | NPSR1 (0.56) | NPSR1APEX1TOP2AKDM4ERECQL | |
| SCHEMBL24507621 | 0.82 | TSHR (0.51) | NPSR1APEX1TOP2AKDM4ERECQL | |
| Hydrochloric Acid SCHEMBL28877037 | 0.81 | KDM4E (0.66) | NPSR1APEX1TOP2AKDM4ERECQL | |
| SCHEMBL31695078 | 0.81 | APEX1 (0.59) | NPSR1APEX1TOP2AKDM4ERECQL | |
| SCHEMBL6473944 | 0.79 | APEX1 (0.79) | NPSR1APEX1TOP2AKDM4ERECQL | |
| SCHEMBL10893426 | 0.79 | NPSR1 (0.54) | NPSR1APEX1TOP2AKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978750-A2 | \"SYNTHESIS OF DABIGATRAN\ | USV Limited (IN) | 2016-02-03 | — | — | EP | claimed |
| WO-2014167577-A2 | \"SYNTHESIS OF DABIGATRAN\ | USV LIMITED (IN) | 2014-10-16 | — | — | WO | claimed |
| EP-2978750-A2 | \"SYNTHESIS OF DABIGATRAN\ | USV Limited (IN) | 2016-02-03 | — | — | EP | disclosed |
| WO-2014167577-A2 | \"SYNTHESIS OF DABIGATRAN\ | USV LIMITED (IN) | 2014-10-16 | — | — | WO | disclosed |