SCHEMBL161691

SCHEMBL161691

C/C(=C\C(F)(F)C(C)(F)F)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.31
AKR1C3 P42330 1/20 0.31
GRIK1 P39086 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL345299 1.00 PTGS1 (0.31) PTGS1AKR1C3GRIK1
SCHEMBL312631 0.86
SCHEMBL312630 0.86
SCHEMBL224413 0.85
SCHEMBL532588 0.85
SCHEMBL6216639 0.83 PTGS1 (0.32) PTGS1AKR1C3
SCHEMBL225194 0.83 PTGS1 (0.32) PTGS1AKR1C3
SCHEMBL5193760 0.83
SCHEMBL3382354 0.83
SCHEMBL3792602 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4182737-B1 OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2024-07-03 EP claimed
EP-3850018-B1 ANTIMICROBIAL CONTACT LENSES KERAMED INC (US) 2023-08-23 EP claimed
EP-3728339-B1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS AMO Ireland (IE) 2022-07-06 EP claimed
EP-3490802-B1 METHOD OF INKJET PRINTING AND FIXING COMPOSITION HEWLETT PACKARD DEVELOPMENT CO (US) 2021-08-11 EP claimed
EP-3077429-B1 SOFT HYDROPHOBIC ACRYLIC MATERIALS NOVARTIS AG (CH) 2018-09-26 EP claimed
US-9469763-B2 Photo-curable organic-inorganic hybrid resin composition DONGJIN SEMICHEM CO., LTD. (KR) 2016-10-18 US claimed
US-8936744-B2 Photocurable resin composition containing fluorine and method for producing a resin mold using same DONGJIN SEMICHEM CO., LTD. (KR) 2015-01-20 US claimed
US-20140135413-A1 PHOTO-CURABLE ORGANIC-INORGANIC HYBRID RESIN COMPOSITION DONGJIN SEMICHEM CO., LTD. (KR) 2014-05-15 US claimed
US-8703238-B2 Curable inkjet ink set and methods for inkjet printing AGFA GRAPHICS NV (BE) 2014-04-22 US claimed
US-8197058-B2 Set of curable liquids and methods for inkjet printing AGFA GRAPHICS NV (BE) 2012-06-12 US claimed
EP-0588534-B1 Radiation curing ink HAYAKAWA RUBBER (JP) 1998-12-02 EP claimed
EP-0588533-B1 Printed thermoplastic resin products and method for printing such products HAYAKAWA RUBBER (JP) 1998-08-12 EP claimed
EP-0722387-A1 ORGANIC OPTICAL COMPONENTS AND PREPARATION THEREOF Epigem Limited (GB) 1996-07-24 EP claimed
US-5496675-A Carrier coating and processes XEROX CORPORATION (US) 1996-03-05 US claimed
EP-0683798-A1 CYCLO-OLEFIN COPOLYMERS WITH HIGH TENACITY AND LOW OPTICAL ATTENUATION HOECHST AKTIENGESELLSCHAFT (DE) 1995-11-29 EP claimed
EP-0683797-A1 CYCLO-OLEFIN COPOLYMERS WITH LOW FUSION VISCOSITY AND LOW OPTICAL ATTENUATION HOECHST AKTIENGESELLSCHAFT (DE) 1995-11-29 EP claimed
WO-1995009726-A1 ORGANIC OPTICAL COMPONENTS AND PREPARATION THEREOF EPIGEM LTD (GB) 1995-04-13 WO claimed
WO-1994018252-A1 CYCLO-OLEFIN COPOLYMERS WITH HIGH TENACITY AND LOW OPTICAL ATTENUATION HOECHST AKTIENGESELLSCHAFT (DE) 1994-08-18 WO claimed
WO-1994018251-A1 CYCLO-OLEFIN COPOLYMERS WITH LOW FUSION VISCOSITY AND LOW OPTICAL ATTENUATION HOECHST AKTIENGESELLSCHAFT (DE) 1994-08-18 WO claimed
US-5270415-A Balanced charge polymer and hydrophilic contact lens manufactured therefrom ALLERGAN INC. (US) 1993-12-14 US claimed