SCHEMBL16171983

SCHEMBL16171983

Cc1ccc(Oc2ccc(OC3(c4ccc(Oc5ccc(C)cc5)cc4)CCC4(C)C(CCC5C4CCC4(C)C(C(C)CCCC(C)C)CCC54)C3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.51
CYP2C19 P33261 1/20 0.51
INPP5D Q92835 1/20 0.50
CDC25A P30304 4/20 0.47
POLA1 P09884 1/20 0.47
SRD5A1 P18405 4/20 0.46
SRD5A2 P31213 3/20 0.44
ATIC P31939 1/20 0.43
NPC1L1 Q9UHC9 1/20 0.42
OSBP P22059 2/20 0.41
OSBP2 Q969R2 2/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
ABCB1 P08183 1/20 0.41
RORC P51449 1/20 0.41
CYP46A1 Q9Y6A2 1/20 0.41
FOLH1 Q04609 1/20 0.41
FNTA P49354 2/20 0.41
FNTB P49356 2/20 0.41
GRIN2A Q12879 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12577483 1.00 CYP2D6 (0.51) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL1688873 0.89 CYP2D6 (0.53) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL15501493 0.84 CYP2D6 (0.43) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL105651 0.83 CDC25A (0.57) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL10054763 0.82 CYP2D6 (0.55) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL12172548 0.80 CYP2D6 (0.51) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL12709797 0.80 CDC25A (0.54) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL15043321 0.79 GPBAR1 (0.41) CYP2D6CYP2C19INPP5DCDC25AUSP2
SCHEMBL17208297 0.79 CDC25A (0.53) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL13891768 0.78 CYP2D6 (0.51) CYP2D6CYP2C19INPP5DCDC25APOLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9465244-B2 Liquid crystal display SONY CORPORATION (JP) 2016-10-11 US disclosed
US-20140307211-A1 LIQUID CRYSTAL DISPLAY SONY CORPORATION (JP) 2014-10-16 US disclosed