Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.59 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.59 |
| ▸ | SCN2B | O60939 | 1/20 | 0.59 |
| ▸ | SCN1A | P35498 | 1/20 | 0.59 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16175258 | 0.95 | SCN9A (0.67) | SCN9ASCN5ASCN2BSCN1ASCN1B | |
| SCHEMBL371093 | 0.91 | SCN9A (0.67) | SCN9ASCN5ASCN2BSCN1ASCN1B | |
| SCHEMBL16175056 | 0.90 | SCN9A (0.61) | SCN9ASCN5ASCN2BSCN1ASCN1B | |
| SCHEMBL16175293 | 0.88 | SCN9A (0.59) | SCN9ASCN5ASCN2BSCN1ASCN1B | |
| SCHEMBL16175049 | 0.88 | SCN9A (0.73) | SCN9ASCN5ASCN2BSCN1ASCN1B | |
| SCHEMBL16174924 | 0.86 | SCN9A (0.66) | SCN9ASCN5ASCN2BSCN1ASCN1B | |
| SCHEMBL16175149 | 0.85 | SCN9A (0.68) | SCN9ASCN5ASCN2BSCN1ASCN1B | |
| SCHEMBL16175470 | 0.85 | SCN9A (0.59) | SCN9ASCN5ASCN2BSCN1ASCN1B | |
| SCHEMBL16175286 | 0.83 | SCN9A (0.67) | SCN9ASCN5ASCN2BSCN1ASCN1B | |
| SCHEMBL16175074 | 0.82 | SCN9A (0.64) | SCN9ASCN5ASCN2BSCN1ASCN1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593432-B1 | N-SULFONYLBENZAMIDE DERIVATIVES USEFUL AS VOLTAGE GATED SODIUM CHANNEL INHIBITORS | PFIZER LTD (GB) | 2014-10-22 | — | — | EP | disclosed |