Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.51 |
| ▸ | SCN2B | O60939 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16175265 | 0.90 | SCN9A (0.58) | SCN9ASCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL16175204 | 0.84 | SCN9A (0.53) | SCN9ASCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL16175086 | 0.81 | SCN9A (0.51) | SCN9ASCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL364362 | 0.81 | SCN9A (0.55) | SCN9ASCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL16175376 | 0.78 | SCN9A (0.53) | SCN9ASCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL16175165 | 0.78 | SCN9A (0.55) | SCN9ASCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL16175348 | 0.77 | SCN9A (0.54) | SCN9ASCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL16175122 | 0.76 | SCN9A (0.50) | SCN9ASCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL366574 | 0.75 | SCN9A (0.56) | SCN9ASCN5A | |
| SCHEMBL365905 | 0.74 | SCN9A (0.61) | SCN9ASCN2BSCN1ASCN1BSCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593432-B1 | N-SULFONYLBENZAMIDE DERIVATIVES USEFUL AS VOLTAGE GATED SODIUM CHANNEL INHIBITORS | PFIZER LTD (GB) | 2014-10-22 | — | — | EP | disclosed |